Focal giant cell lesion in the wall of a radicular cyst
Abstract
A rare case of unilocular radiolucency associated with the apices of the left maxillary incisor and canine in a female aged 32 years, is presented. Histologically, the lesion showed foci of giant cell lesion in the wall of radicular cyst; there was no evidence of hyperparathyroidism. The clinicopathological presentation is likely a histopathological curiosity; and may be an example of “double” pathology / collision of apical inflammatory pathology and central giant cell lesion or reflect florid osteoclastic resorption. Indiscriminate use of the term “periapical central giant cell lesion (granuloma)” in histopathological diagnosis should be avoided.
Keywords
Full Text:
READ AS PDFReferences
Economopoulou P, Triantafyllou A. Pathobiology of radicular unilocular radiolucencies. Stomatologia 2007;64(1): 3-37.
Dahlkemper P, Wolcott JF, Pringle GA, Hicks ML. Periapical central giant cell granuloma: a potential endodontic diagnosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;90(6): 39-45.
Jundt G. Central giant cell lesion. In: Barnes L, Eveson JW, Reichart P, Sidransky D (eds). World Health Organization Classification of Tumours. Pathology and Genetics of Head and Neck Tumours. IARC Press, Lyon, 2005: 324.
Kuc I, Peters E, Pan J: Comparison of clinical and histologic diagnoses in periapical lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89(3): 333-337.
Nary Filho H, Matsumoto MA, Fraga SC, Gonçales ES, Sérvulo F. Periapical radiolucency mimicking an odontogenic cyst. Int Endod J 2004;37(5): 337-344.
Lombardi T, Bischof M, Nedir R, Vergain D, Galgano C, Samson J, Küffer R: Periapical central giant cell granuloma misdiagnosed as odontogenic cyst. Int Endod J 2006;39(6): 510-515.
Ortega A, Fariña V, Gallardo A, Espinoza I, Acosta S. Nonendodontic periapical lesions: a retrospective study in Chile. Int Endod J 2007;40(5): 386-390.
Koivisto T, Bowles WR, Rohrer M. Frequency and distribution of radiolucent jaw lesions: a retrospective analysis of 9,723 cases. J Endod 2012;38(6): 729-732.
Sirotheau Corrêa Pontes F, Paiva Fonseca F, Souza de Jesus A, Garcia Alves AC, Marques Araújo L, Silva do Nascimento L, Rebelo Pontes HA. Nonendodontic lesions misdiagnosed as apical periodontitis lesions: series of case reports and review of literature. J Endod 2014;40(1): 16-27.
Economopoulou P, Hatzimanolis P. "Hybrid" odontogenic fibroma - giant cell granuloma lesion of the mandible. Report of a case. Stomatologia 2004;61(2): 76-83.
Refbacks
- There are currently no refbacks.
Copyright 2015-2017, Hellenic Society of Pathology
ISSN: 2459-3443